We are seeking quotes for vaccine medical countermeasures (vaccines, antigens, and adjuvants) for pandemic influenza preparedness and response for BARDA.
Scope of work: Produce antigens, adjuvants, and vaccines against influenza or other pandemic-potential viruses as BARDA requires, including during a public health emergency.
Vaccine improvement: Produce antigens, adjuvants, and/or vaccines to support USG efforts to improve influenza vaccines where feasibility data exists.
Regulatory support: Generate and submit to FDA all relevant analytical, nonclinical, clinical, and CMC data, including data generated during interpandemic periods.
Contractor furnishes: Provide all services, qualified personnel, materials, supplies, equipment, and facilities not provided by the USG; U.S. facilities are preferred.
Mandatory qualification: Must produce vaccines against influenza and strains with pandemic potential.
Required experience: Must hold a U.S. influenza vaccine license, or have developed an influenza vaccine shown by a submitted Biologics License Application (BLA) for seasonal or pandemic influenza vaccine.
The basics
Price due
October 30, 2026
Where
Washington, D.C.
Buyer
Health and Human Services, Barda Aspr Daappo Barda Dcma
We read the solicitation documents for this bid (12 documents, 388 pages). Each item shows the file and page it came from. Check the original documents and any addenda before you bid.
How to submit
Subcontracting reports (ISRs and SSRs) shall be submitted via the Electronic Subcontracting Reporting System (eSRS) website. (Attachment 12, p. 1)
Set-aside and participation goals
HHS expects subcontracting plans to meet at least these goals: Small Business 33.00%, Small Disadvantaged 5.00%, Women Owned 5.00%, Service Disabled Veteran Owned 3.00%, HUBZone 3.00%. (Attachment 12, p. 1)
A Subcontracting Plan is required if the estimated contract cost may exceed $700,000 ($1,500,000 for construction). Small businesses are excluded. (Attachment 12, p. 1)
Forms to return
Attachment 3: Vendor Production Facilities: Formulation, Fill-Finish (RFP#75A50126R00001). (Attachment 3, p. 5)
Attachment 2: ASPR Security Requirements; proposals must include a statement attesting to intent and ability to comply with the security requirements. (Attachment 6, p. 1)
Attachment 15 - Contractor (Vaccine MCMs for Pandemic Influenza Preparedness questionnaire). (Attachment 9, p. 2)
HHS Subcontracting Plan Template, including a Signature Page. (Attachment 12, p. 1)
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Recent comparable awards for similar work — not necessarily this exact solicitation's history.
Want to bid it yourself?
You can, and it is free. Go to SAM.gov, search for solicitation 75A50126R00001_RFP_NPIVS_27, and submit before October 30, 2026. You will need your own account on that site and an active SAM.gov registration.